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USC-OGP 2-DE database

Two-dimensional polyacrylamide gel electrophoresis database


USC-OGP 2-DE database 
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Searching in 'USC-OGP 2-DE database' for entry matching: GALK1_HUMAN




USC-OGP 2-DE database:  GALK1_HUMAN


GALK1_HUMAN


General information about the entry
View entry in simple text format
Entry nameGALK1_HUMAN
Primary accession numberP51570
integrated into USC-OGP 2-DE database on January 17, 2017 (release 1)
2D Annotations were last modified onJanuary 17, 2017 (version 1)
General Annotations were last modified on April 5, 2017 (version 2)
Name and origin of the protein
DescriptionRecName: Full=Galactokinase; EC=2.7.1.6; AltName: Full=Galactose kinase;.
Gene nameName=GALK1
Synonyms=GALK
Annotated speciesHomo sapiens (Human) [TaxID: 9606]
TaxonomyEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo.
References
[1]   2D GEL CHARACTERIZATION
Author 1., Author 2.
Submitted (Mar-2011) to Current
2D PAGE maps for identified proteins
How to interpret a protein

PLATELET_4-7 {PLATELET 4-7}
Homo sapiens (Human)
PLATELET_4-7
  map experimental info
 
PLATELET_4-7

MAP LOCATIONS:
pI=5.90; Mw=40609



PLATELET_5-6 {PLATELET 5-6}
Homo sapiens (Human)
PLATELET_5-6
  map experimental info
 
PLATELET_5-6

MAP LOCATIONS:
pI=5.89; Mw=40117



PLATELET_6-11 {PLATELET 6-11}
Homo sapiens (Human)
PLATELET_6-11
  map experimental info
 
PLATELET_6-11

MAP LOCATIONS:
pI=5.81; Mw=40264



UVEAL_MELANOMA_3-10 {UVEAL MELANOMA 3-10}
Homo sapiens (Human)
UVEAL_MELANOMA_3-10
  map experimental info
 
UVEAL_MELANOMA_3-10

MAP LOCATIONS:
pI=6.19; Mw=41038
pI=6.41; Mw=40578

Cross-references
UniProtKB/Swiss-ProtP51570; GALK1_HUMAN.



2D PAGE maps for identified proteins
  • How to interpret a protein map
  • You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw.
  • Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly.
  • Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed.



External data extracted from UniProtKB/Swiss-Prot
Extracted from UniProtKB/Swiss-Prot, release: 0.0
Entry nameGALK1_HUMAN
Primary accession numberP51570
Secondary accession number(s) B2RC07 B4E1G6
Sequence was last modified on October 1, 1996 (version 1)
Annotations were last modified on March 15, 2017 (version 174)
Name and origin of the protein
DescriptionRecName: Full=Galactokinase; EC=2.7.1.6; AltName: Full=Galactose kinase;
Gene nameName=GALK1
Synonyms=GALK
Encoded onName=GALK1; Synonyms=GALK
Keywords3D-structure; Alternative splicing; ATP-binding; Carbohydrate metabolism; Cataract; Complete proteome; Direct protein sequencing; Disease mutation; Galactose metabolism; Kinase; Nucleotide-binding; Phosphoprotein; Polymorphism; Reference proteome; Transferase.
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License
Cross-references
EMBLU26401; AAA96147.1; -; mRNA
EMBLL76927; AAB51607.1; -; Genomic_DNA
EMBLAK303832; BAG64778.1; -; mRNA
EMBLAK314890; BAG37404.1; -; mRNA
EMBLBT007005; AAP35651.1; -; mRNA
EMBLAC087749; -; NOT_ANNOTATED_CDS; Genomic_DNA
EMBLCH471099; EAW89316.1; -; Genomic_DNA
EMBLBC001166; AAH01166.1; -; mRNA
CCDSCCDS11728.1; -. [P51570-1]; .
RefSeqNP_000145.1; NM_000154.1. [P51570-1]; .
UniGeneHs.407966; -; .
PDB1WUU; X-ray; 2.50 A; A/B/C/D=2-392
PDB1YH7; Model; -; A=1-392
PDBsum1WUU; -; .
PDBsum1YH7; -; .
ProteinModelPortalP51570; -; .
SMRP51570; -; .
BioGrid108857; 16; .
IntActP51570; 16; .
MINTMINT-4999410; -; .
STRING9606.ENSP00000225614; -; .
BindingDBP51570; -; .
ChEMBLCHEMBL1293257; -; .
DrugBankDB04395; Phosphoaminophosphonic Acid-Adenylate Ester; .
iPTMnetP51570; -; .
PhosphoSitePlusP51570; -; .
BioMutaGALK1; -; .
DMDM1730187; -; .
OGPP51570; -; .
REPRODUCTION-2DPAGEIPI00019383; -; .
EPDP51570; -; .
PaxDbP51570; -; .
PeptideAtlasP51570; -; .
PRIDEP51570; -; .
DNASU2584; -; .
EnsemblENST00000225614; ENSP00000225614; ENSG00000108479. [P51570-1]; .
EnsemblENST00000588479; ENSP00000465930; ENSG00000108479. [P51570-1]; .
GeneID2584; -; .
KEGGhsa:2584; -; .
CTD2584; -; .
DisGeNET2584; -; .
GeneCardsGALK1; -; .
HGNCHGNC:4118; GALK1; .
HPAHPA007094; -; .
HPAHPA016960; -; .
MalaCardsGALK1; -; .
MIM230200; phenotype; .
MIM604313; gene; .
neXtProtNX_P51570; -; .
OpenTargetsENSG00000108479; -; .
Orphanet79237; Galactokinase deficiency; .
PharmGKBPA28533; -; .
eggNOGKOG0631; Eukaryota; .
eggNOGCOG0153; LUCA; .
GeneTreeENSGT00530000063433; -; .
HOGENOMHOG000241100; -; .
HOVERGENHBG051695; -; .
InParanoidP51570; -; .
KOK00849; -; .
OMARREECAQ; -; .
OrthoDBEOG091G06HT; -; .
PhylomeDBP51570; -; .
TreeFamTF354326; -; .
BRENDA2.7.1.6; 2681; .
ReactomeR-HSA-70370; Galactose catabolism; .
SABIO-RKP51570; -; .
UniPathwayUPA00214; -; .
EvolutionaryTraceP51570; -; .
GenomeRNAi2584; -; .
PROPR:P51570; -; .
ProteomesUP000005640; Chromosome 17; .
BgeeENSG00000108479; -; .
CleanExHS_GALK1; -; .
ExpressionAtlasP51570; baseline and differential; .
GenevisibleP51570; HS; .
GOGO:0005737; C:cytoplasm; IDA:UniProtKB; .
GOGO:0005829; C:cytosol; TAS:Reactome; .
GOGO:0070062; C:extracellular exosome; IDA:UniProtKB; .
GOGO:0016020; C:membrane; IDA:UniProtKB; .
GOGO:0005524; F:ATP binding; IDA:UniProtKB; .
GOGO:0004335; F:galactokinase activity; IDA:UniProtKB; .
GOGO:0005534; F:galactose binding; IDA:UniProtKB; .
GOGO:0019402; P:galactitol metabolic process; IEA:Ensembl; .
GOGO:0019388; P:galactose catabolic process; TAS:Reactome; .
GOGO:0006012; P:galactose metabolic process; IMP:UniProtKB; .
GOGO:0061623; P:glycolytic process from galactose; IEA:Ensembl; .
Gene3D3.30.230.10; -; 1; .
Gene3D3.30.70.890; -; 1; .
InterProIPR000705; Galactokinase; .
InterProIPR019741; Galactokinase_CS; .
InterProIPR019539; GalKase_gal-bd; .
InterProIPR013750; GHMP_kinase_C_dom; .
InterProIPR006204; GHMP_kinase_N_dom; .
InterProIPR006203; GHMP_knse_ATP-bd_CS; .
InterProIPR006206; Mevalonate/galactokinase; .
InterProIPR020568; Ribosomal_S5_D2-typ_fold; .
InterProIPR014721; Ribosomal_S5_D2-typ_fold_subgr; .
PANTHERPTHR10457:SF17; PTHR10457:SF17; 1; .
PfamPF10509; GalKase_gal_bdg; 1; .
PfamPF08544; GHMP_kinases_C; 1; .
PfamPF00288; GHMP_kinases_N; 1; .
PIRSFPIRSF000530; Galactokinase; 1; .
PRINTSPR00473; GALCTOKINASE; .
PRINTSPR00959; MEVGALKINASE; .
SUPFAMSSF54211; SSF54211; 1; .
SUPFAMSSF55060; SSF55060; 1; .
TIGRFAMsTIGR00131; gal_kin; 1; .
PROSITEPS00106; GALACTOKINASE; 1; .
PROSITEPS00627; GHMP_KINASES_ATP; 1; .



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Database constructed and maintained by Angel Garcia, using the Make2D-DB II package (ver. 3.10.2) from the World-2DPAGE Constellation of the ExPASy web server

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